I have battled arthritis ever since a drunk hit me on my motorcycle when I was 17 years old. I use several things to help me and no drugs. Cissus Quadrangularis extract helps me greatly. I also use boswellia, MSM, Tart Cherry, and fish oil. I use much higher dosages than in any combo product. I take fenugreek and use Tribulus Terrestris extract to improve testosterone markers, seems to do wonders.